A team led by Helmholtz Munich scientist Dr. Grzegorz Popowicz unveils the Molecular Interactions Structurally Optimized (MISATO) dataset, offering a transformative approach to training AI models for designing new drug molecules. MISATO represents a…
A team of Helmholtz Munich scientists has made a significant advancement in the understanding of ferroptosis, a complex form of cell death, by successfully detecting it retrospectively in human pathological conditions. This pioneering research,…
At the helm of a new era in vascular research, Prof. Matthias Meier and his team at the Helmholtz Pioneer Campus (HPC) at Helmholtz Munich, introduce a cutting-edge microfluidic vessel-on-chip technology. This innovation leverages human stem cells to…
Scientists have created a non-invasive technology for measuring glucose levels in blood.
After weight loss, people with overweight and obesity express more of the protein Kallistatin* in subcutaneous white adipose tissue. This was demonstrated by researchers from Helmholtz Munich and the German Center for Diabetes Research (DZD) in a…
Various tissue fibroblast types with distinct properties shape the architecture of the specialized niches of the lung (e.g. airways, alveoli, vasculature). In a significant breakthrough, a team led by Gerald Burgstaller and Herbert Schiller from…
A new study led by Helmholtz Munich scientists Ursula Zimber-Strobl and Lothar J. Strobl sheds light on the intricate pathways of B-lymphocyte development during adaptive immune responses. The study, published in Nature Communications, reveals that…
A precursor of cholesterol, previously categorised as harmful, can protect cancer cells from cell death. This finding, published in Nature, opens new doors for cancer research.
Researchers around Magdalena Götz from Helmholtz Munich have made strides in direct neuronal reprogramming. This innovative approach transforms non-neuronal cells, specifically astrocytes, into functional neurons. Investigating patient-derived cells,…
Metabolomics is a scientific approach that involves the comprehensive study of small molecules, known as metabolites, within a biological system. In a major stride towards advancing metabolomics research, researchers around Michael Witting from the…
Epstein-Barr Virus (EBV) is widespread and very contagious: according to the World Health Association more than 90 percent of the global population are infected with this virus throughout their lives. The virus causes B and T cell lymphomas (cancer…
A recent discovery led by Helmholtz Munich researchers from the Type 1 Diabetes Immunology Research Unit has uncovered how regulatory immune T-cells (called Tregs) interplay and control metabolic tissues. The new findings published in Cell…
Therapeutic antibodies play a crucial role in treating diseases by modifying immune cells. Scientists from the Institute of AI for Health at Helmholtz Munich in collaboration with Roche present an open-source framework for comprehensive antibody…
Sporadic Parkinson's Disease (sPD) is a progressive neurodegenerative disorder influenced by both genetic and environmental factors. While mitochondrial dysfunction contributes to this condition, its role across disease progression remains unclear.…
Scientists from the Bonev Lab at the PioneerCampus at Helmholtz Munich present 3DRAM-seq, a revolutionary technique that maps spatial genome organization, chromatin accessibility, DNA methylation, and gene expression - all at once.
A groundbreaking study now published in Nature Genetics marks a turning point in depression genetics, offering new hope for personalized medicine through enhanced Polygenic Risk Scores (PRS).
Helmholtz Munich researchers have discovered, that air pollutants activate previously dormant herpes viruses leading to a immune response. These new findings are now published in ASC Nano.
Scientists from the PioneerCampus at Helmholtz Munich unraveled rather transcriptionally distinct subgroups of human hepatocytes with relevance to human disease and personalized treatment.
Understanding ferroptosis is essential for addressing degenerative diseases and certain cancers. Researchers, led by Dr. Kamyar Hadian from Helmholtz Munich, revealed that the Farnesoid X Receptor (FXR), activated by bile acids, serves as a master…
Chronic obstructive pulmonary disease (COPD) was in 2019 the primary cause of deaths from chronic respiratory diseases, accounting for 3.3 million deaths worldwide. In Germany, according to the “European Lung White Book”, the number of COPD patients…
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